TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells
J. Clin. Invest. Grace Soong, et al. 113:1482 doi:10.1172/JCI20773 [
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Figure 3Surface colocalization of MyD88, IRAK-1, and TRAF6 with TLR2 confirmed by confocal microscopy. After stimulation with
S. aureus, permeabilized cells were stained with the kinases, each labeled with an Alexa Fluor 488–tagged secondary antibody (green). All were found at the cell surface, colocalized (yellow) with TLR2, labeled with an Alexa Fluor 594–tagged secondary antibody (red).
