Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction
J. Clin. Invest. Sara Weis, et al. 113:885 doi:10.1172/JCI20702 [
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Figure 6Platelet aggregates impair blood flow through occluded vessels. (A–F) Microvessels containing rbc’s and platelet aggregates that protrude narrow extensions through (A and B) or interact with (C–F) discontinuous endothelium (arrows). P*, platelets appearing to directly contact basement membrane. Some platelets appear to be degranulated and/or have a less rounded shape, consistent with platelet activation. The platelet aggregates appear as five to eight platelets in plane of section and impede flow through part (A and B), most (C and D), or all (E and F) of the vessel lumen. Scale bars: 1 μm (B) and 500 nm (D–F).
