Quorum sensing in Staphylococcus infections
J. Clin. Invest. Jeremy M. Yarwood, et al. 112:1620 doi:10.1172/JCI20442 [
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Figure 1The accessory gene regulator (
agr) system in
Staphylococcus. The P2 operon encodes (via RNAII) the signaling mechanism, whereas the transcript of the P3 operon, RNAIII, acts as the effector molecule of the
agr locus. Additional regulators of the quorum response and virulence genes, described in the text, are listed. Potential regulatory pathways used by environmental signals are indicated by the dashed red lines.