Bacterial flagellin is a dominant antigen in Crohn disease
J. Clin. Invest. Michael J. Lodes, et al. 113:1296 doi:10.1172/JCI20295 [Go to this article.]

Figure 7
Dose response of CD4⁺ T cell proliferation to CBir1 and Fla-X in multiple strains of mice. Left panel: C3H/HeJ (open triangles), C3H/HeJBir (squares), and C3H/HeJBir.IL-10^–/– (circles). Right panel: FVB (diamonds) and mdr1a^–/– (filled triangles). The y axes indicate sample counts per minute (cpm) minus control T cell plus APC cpm (Ø cpm) for each experimental group. The x axes indicate the dose (∝g/ml) of recombinant flagellin used in each assay. Vertical bars indicate plus or minus one standard deviation of the mean value.