Central and peripheral actions of somatostatin on the growth hormone–IGF-I axis
J. Clin. Invest. Robert D. Murray, et al. 114:349 doi:10.1172/JCI19933 [Go to this article.]

Figure 5
Hepatocyte GH signaling. (A) Western blot analysis of 50 μg protein from primary rat hepatocytes treated with GH in the absence or presence of SRIF for 1–30 minutes. Membranes were blotted for phospho-ERK (pERK; upper panel, 42 kDa) and ERK (lower panel). (B) Northern blot analysis of RNA from cultured primary hepatocytes treated with vehicle, GH, or GH in the presence of SRIF or octreotide for 30 minutes. Membranes were probed for c-myc (upper panel), stripped, and reprobed for GAPDH to correct for loading.