Th2-predominant inflammation and blockade of IFN-γ signaling induce aneurysms in allografted aortas
J. Clin. Invest. Koichi Shimizu, et al. 114:300 doi:10.1172/JCI19855 [Go to this article.]

Figure 4
Metalloproteinase expression during AAA development. The MMP mRNA levels of aortic allografts from WT (white bars), GRKO (black bars), or DKO (gray bars) recipients (n = 6, each). Total RNA was extracted from the aortic allografts and first-strand cDNA generated by reverse transcription was subjected to real-time quantitative PCR with the LightCycler. Data represent the mean ± SEM of six determinations of the percentage of mRNA copies relative to untreated growing cells. *P < 0.05; **P < 0.01; ***P < 0.001.