Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis
J. Clin. Invest. Ivan J. Fuss, et al. 113:1490 doi:10.1172/JCI19836 [Go to this article.]

Figure 6
Cytotoxicity of NKT cells. In these studies HT-29 epithelial cells were prestimulated with LPS (see Methods) to induce increased expression of CD1d (data not shown). (A) Invariant NKT cells were cultured with target HT-29 cells in the presence or absence of IL-13 Ab (see Methods), and the percentage of cytotoxicity was measured by the CytoTox 96 System (n = 4 experiments). Error bars represent SEMs. (B) Purified UC lamina propria (LP) CD4⁺CD161⁺T cells were cultured as in A. (C) Purified CD LP CD4⁺CD161⁺ T cells were cultured as in A. For both B and C, n = 2 experiments. Error bars represent SDs.