Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells
J. Clin. Invest. Robert E. Hunger, et al. 113:701 doi:10.1172/JCI19655 [
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Figure 4Comparison of antigen presentation by LC-like DCs and MD-DCs. LC-like DCs (filled symbols) or MD-DCs (open symbols) were incubated with T cells in the presence of the indicated amount of
M. leprae or
M. tuberculosis sonicates. (A) Proliferation was measured as described for Figure
2. (B) IFN-γ production was measured as described in Methods. The values shown are the mean ± SEM of triplicate cultures and are representative of at least three independent experiments.
