Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice
J. Clin. Invest. Yanhua Hu, et al. 113:1258 doi:10.1172/JCI19628 [Go to this article.]

Figure 6
Creation of chimeric mice and culture of adventitial cells. Femurs of chimeric mice with ROSA26 or wild-type bone marrow were harvested and transplanted. Sections of the aortic root from chimeric mice with ROSA26 (A) or wild-type (B) bone marrow were stained with X-gal. (C and D) Cultured adventitial cells from chimeric mice with ROSA26 bone marrow (C) or SM-LacZ mice with wild-type bone marrow (D). Cells were stimulated with PDGF-BB (10 ng/ml) for 3 days and stained with β-gal. Arrows indicate β-gal⁺ cells.