Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice
J. Clin. Invest. Yanhua Hu, et al. 113:1258 doi:10.1172/JCI19628 [
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Figure 1Immunohistochemical staining. Aortic roots from ApoE
_/_ mice were sectioned and labeled with a variety of antibodies as indicated. Sections were developed with alkaline phosphatase anti-alkaline phosphatase (APAAP) techniques and counterstained with hematoxylin (blue). Total cells and positive cells were counted under the microscope. Arrows indicate intima and media (
A and
C) or examples of positive cells (
D, red). (
A) The aortic wall. (
B) A heart section. (
C) The aortic root region.
A_
C were labeled with Sca-1 antibody and photographed at lower magnification. (
D) Sections from aortic root regions at a higher magnification. (
E) The graph shows data of means (± SEM) from eight animals per group.
