Stat-3 is required for pulmonary homeostasis during hyperoxia
J. Clin. Invest. Isamu Hokuto, et al. 113:28 doi:10.1172/JCI19491 [
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Figure 3Kaplan-Meier plot of survival of
Stat-3Δ/Δ and control mice during hyperoxia. Adult
Stat-3Δ/Δ mice and littermates were exposed to 95% O
2. Survival of
Stat-3Δ/Δ mice in hyperoxia (
n = 13) was significantly decreased compared with littermate, nondeleted controls (
n = 14).
P < 0.001 by log-rank test.