The endogenous cannabinoid system protects against colonic inflammation
J. Clin. Invest. Federico Massa, et al. 113:1202 doi:10.1172/JCI19465 [
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Figure 3Pharmacological stimulation of cannabinoid receptors and genetic enhancement of endocannabinoid levels protect against DNBS-induced colitis. (A and B) Macroscopic score of colonic inflammation (A) and levels of MPO activity (B) in vehicle-treated and HU210-treated (0.05 mg/kg) C57BL/6N mice. (C and D) Macroscopic score of colonic inflammation (C) and levels of MPO activity (D) in
FAAH+/+ and
FAAH–/– mice. Data are means ± SEM.
