The endogenous cannabinoid system protects against colonic inflammation
J. Clin. Invest. Federico Massa, et al. 113:1202 doi:10.1172/JCI19465 [Go to this article.]

Figure 1
DNBS- and DSS-induced colitis is worsened in CB1^–/– and in SR141716A-treated (3 mg/kg) C57BL/6N mice. (A and B) Macroscopic score of colonic inflammation (A) and levels of MPO activity (B) in CB1^+/+ and CB1^–/– littermates. (C and D) Macroscopic score of colonic inflammation (C) and levels of MPO activity (D) in vehicle- and SR141716A-treated C57BL/6N mice. Data are means ± SEM.