Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
J. Clin. Invest. Haiyan Xu, et al. 112:1821 doi:10.1172/JCI19451 [
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Figure 6The expression of
ADAM8,
MIP-1α,
MCP-1,
MAC-1,
F4/80, and
CD68 in
ob/ob WAT treated with rosiglitazone. Twelve-week-old
ob/ob mice were treated with either 15 mg/kg rosiglitazone (Rosi) or vehicle (sterile water; Veh) for 28 consecutive days (
n = 10 in each group). For comparison, the expression level in rosiglitazone-treated
ob/ob mice was arbitrarily set at 1; error bars represent ± SE; *
P < 0.05.
y axes show arbitrary units representing relative expression levels of mRNAs.
