Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
J. Clin. Invest. Haiyan Xu, et al. 112:1821 doi:10.1172/JCI19451 [
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Figure 4The mRNA expression of
ADAM8,
MIP-1α,
MCP-1,
MAC-1,
F4/80, and
CD68 in stromal-vascular and adipocyte fractions. For quality control, leptin was examined in these samples. To compare with the expression of known adipose inflammation genes,
TNF-α and
IKKβ expression was also examined. For genes predominantly expressed in the stromal-vascular fraction, the expression in adipocytes was set at 1; error bars represent ± SE. For leptin, the expression in stromal-vascular cells was set at 1.
y axes show arbitrary units representing relative expression levels of mRNAs.
