Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
J. Clin. Invest. Haiyan Xu, et al. 112:1821 doi:10.1172/JCI19451 [
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Figure 3The transcriptional regulation of
ADAM8,
MIP-1α,
MCP-1,
MAC-1,
F4/80, and
CD68 in macrophage-rich tissues (WAT, lung, and spleen) of
ob/ob and
db/db mice. For comparison, the gene expression level in lean mice was arbitrarily set at 1; error bars represent ± SE.
y axes show arbitrary units representing relative expression levels of mRNAs.
