Importance of minor histocompatibility antigen expression by nonhematopoietic tissues in a CD4+ T cell–mediated graft-versus-host disease model
J. Clin. Invest. Stephen C. Jones, et al. 112:1880 doi:10.1172/JCI19427 [
Go to this article.]
Figure 4Minor histocompatibility antigen expression by nonhematopoietic tissues stimulates lethal GVHD. Established [B6→BALB.B] and [B6→B6] BM chimeras were reirradiated (13 Gy, split dose) and injected with 2 × 10
6 B6 ATBM cells in combination with 2 × 10
7 B6 CD4
+ T cells. Survival of transplanted recipients. Results are expressed as survival of transplanted recients;
n = 5 for B6→[B6→BALB.B], and
n = 4 for B6→[B6→B6].
