AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
J. Clin. Invest. Raymond R. Russell, et al. 114:495 doi:10.1172/JCI19297 [Go to this article.]

Figure 1
Protein expression of the native and mutant catalytic α subunits of AMPK in WT and AMPK KD hearts. Immunoblots showing the expression of native and mutant α isoforms of the catalytic subunit of AMPK in hearts from KD (K45R α2 mutation) and WT mice (A). Immunoblot confirming the expression of the c-myc–tagged transgene in KD hearts (B). Note that the KD transgenic α2 isoform containing the K45R mutation and c-myc tag migrates more slowly than the WT α2 isoform. TG, transgene project.