Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance
J. Clin. Invest. Karsten Sydow, et al. 113:482 doi:10.1172/JCI19267 [
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Figure 5Effects of in vivo and in vitro GTN-treatment on mitochondrial production of ROS as assessed by L-012 enhanced chemiluminescence. Data are mean ± SEM from 4–19 separate experiments. UA, uric acid. *
P < 0.05 vs. control;
#P < 0.05 vs. 50 μM GTN.
