Obesity is associated with macrophage accumulation in adipose tissue
J. Clin. Invest. Stuart P. Weisberg, et al. 112:1796 doi:10.1172/JCI19246 [
Go to this article.]
Figure 7Macrophage-deficient FVB/NJ
Csf1op/op mice are also deficient in F4/80
+ cells in adipose tissue. SVCs were isolated from subcutaneous and perigonadal adipose tissue of macrophage-deficient (FVB/NJ
Csf1op/op) and control (FVB/NJ
Csf1+/+) mice. Flow cytometry of SVCs isolated from two perigondadal adipose tissue depot illustrates that tissue from macrophage-deficient mice (
b) contains 34% the number of F4/80
+ cells found in adipose tissue from control mice (
a).
