Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor–related protein
J. Clin. Invest. Manuel Yepes, et al. 112:1533 doi:10.1172/JCI19212 [
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Figure 6Analysis of Evans blue extravasation following a dose-response study of intraventricular injection of tPA. Quantitative analysis of Evans blue extravasation from brain extracts of WT C57BL/6J mice 1 hour after intraventricular injection of 2.5 μl of increasing concentrations of active tPA.
n = 6 for each point.
