Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor–related protein
J. Clin. Invest. Manuel Yepes, et al. 112:1533 doi:10.1172/JCI19212 [
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Figure 3Dose-response study of neuroserpin treatment following MCAO. Quantitative analysis of Evans blue extravasation from brain extracts 6 hours after MCAO in WT C57BL/6J mice treated with an intraventricular injection of 2.5 μl of either PBS or increasing doses of neuroserpin immediately after MCAO. Analysis was as in Figure
2, and
n = 4–6 for each point.
