Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production
J. Clin. Invest. Meihui Pan, et al. 113:1277 doi:10.1172/JCI19197 [Go to this article.]

Figure 3
DFX or vitamin E restores the secretion of VLDL from McA cells incubated with DHA. McA cells were pretreated with BSA or DHA/BSA for 1 hour, then labeled to steady state in the presence of BSA, DHA/BSA, DHA/BSA plus 100 ∝M DFX, or DHA/BSA plus 120 ∝M vitamin E. Conditioned medium samples were then taken for the quantification of recovered total [35S]-ApoB100 (A), and for sucrose density gradient ultracentrifugation (B). After ultracentrifugation, the density fractions were collected and their ApoB100 contents analyzed as in Figure 1. *P < 0.01 vs. DHA.