The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen
J. Clin. Invest. Seiji Kawamoto, et al. 114:399 doi:10.1172/JCI19082 [Go to this article.]

Figure 5
(A) Serum levels of IgE, IgG1, and IgG2a anti-OVA antibodies in intraperitoneally immunized C3aR^–/– and WT littermates. Horizontal lines represent means. (B and C) Cytokines in supernatants of splenocytes from i.p-immunized C3aR^–/– mice and WT littermates following in vitro stimulation (stim.) with OVA. Pooled results of experiments using five or six mice in each group. Vertical lines and error bars represent mean ± SEM.