The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen
J. Clin. Invest. Seiji Kawamoto, et al. 114:399 doi:10.1172/JCI19082 [
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Figure 4(
A) Number of infiltrating eosinophils and (
B) cytokine expression in sensitized skin of C3aR
–/– mice and WT controls. Levels were normalized to β2-microglobulin. Pooled results of experiments using 6 OVA-sensitized mice and six saline-sensitized controls. Horizontal lines represent mean ± SEM. *
P < 0.05, **
P < 0.01. hpf, high-power field.