Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism
J. Clin. Invest. Takashi Shimada, et al. 113:561 doi:10.1172/JCI19081 [
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Figure 2Histological analysis of bone. (
a) Soft X-rays of femurs prepared from 7-week-old mice. (
b and
c) Villanueva-Goldner stain of undecalcified femurs prepared from 2- and 7-week-old mice. (
b) Distal metaphysis of femurs isolated at 2 weeks (upper) and 7 weeks (lower) of age. Original magnification, ×4. (
c) Growth plates of femurs at 2 weeks (upper) and 7 weeks (lower) of age. Mineralized bone tissues are colored in green, and unmineralized osteoid tissues are shown in orange. Original magnification, ×20.