Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency
J. Clin. Invest. Gilles Faury, et al. 112:1419 doi:10.1172/JCI19028 [
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Figure 3Reactivity of artery segments. Effect of PE and Ach (5 μM, except for the renal artery, which is 1.5 μM) on the ID of the ascending aorta (
a), the abdominal aorta (
b), the carotid artery (
c), and the renal artery (
d). Control is untreated vessel. Values for the
Eln+/– vessel have been normalized to
Eln+/+ control. *Significant difference (
P ≤ 0.05, LSD test) between
Eln+/+ and
Eln+/– vessel responsiveness. #Significant difference (
P ≤ 0.05, LSD test) from the corresponding control vessel. Mean values ± SEM,
n = 4–8 for each vessel type. Gray bars,
Eln+/+; white bars,
Eln+/–.
