Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4+ T cells
J. Clin. Invest. Daphne C. Tsitoura, et al. 113:619 doi:10.1172/JCI18975 [
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Figure 3Stimulation of Dex-treated T cells is not associated with enhanced apoptosis. Dex-treated and control naive CD4+ T cells were stimulated with anti-CD3 or anti-CD3 plus IL-2 and stained with (
a) annexin V and (
b) propidium iodide 24, 48, and 72 hours later. The number of positively stained cells was assessed by flow cytometry. Results are shown as mean ± SD of duplicate samples. Control, medium alone.