Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4+ T cells
J. Clin. Invest. Daphne C. Tsitoura, et al. 113:619 doi:10.1172/JCI18975 [
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Figure 2Costimulation promotes T cell resistance to Dex. Dex-treated and control T cells were stained with CFSE and stimulated with anti-CD3 or anti-CD3 plus IL-2 for 3 days. Cells were harvested before stimulation and on days 1, 2, and 3 and analyzed by flow cytometry. Results from a representative experiment are shown. Filled purple: before stimulation; dashed black line: after 24 hours; pink line: after 48 hours; blue line: after 72 hours.
