Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle
J. Clin. Invest. Jason K. Kim, et al. 113:756 doi:10.1172/JCI18917 [
Go to this article.]
Figure 3Insulin-stimulated whole-body and skeletal muscle (gastrocnemius) glucose metabolic flux in WT (gray bars) and FATP1 KO (black bars) mice with lipid infusion or high-fat feeding. (A) Insulin-stimulated whole-body glycolysis in vivo. (B) Insulin-stimulated whole-body glycogen plus lipid synthesis from glucose in vivo. (C) Insulin-stimulated skeletal muscle glycolysis in vivo. (D) Insulin-stimulated skeletal muscle glycogen synthesis in vivo. Values are means ± SE for 5–6 experiments. *
P < 0.05 versus WT (control) mice.
