Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle
J. Clin. Invest. Jason K. Kim, et al. 113:756 doi:10.1172/JCI18917 [Go to this article.]

Figure 2
Whole-body and tissue-specific glucose uptake in WT (gray bars) and FATP1 KO (black bars) mice with lipid infusion or high-fat feeding. (A) Steady-state glucose infusion rate, obtained from averaged rates of 90 to 120 minutes of hyperinsulinemic-euglycemic clamps. (B) Insulin-stimulated whole-body glucose turnover in vivo. (C) Insulin-stimulated skeletal muscle glucose uptake in vivo. (D) Insulin-stimulated glucose uptake in brown adipose tissue in vivo. Values are means ± SE for 5–6 experiments. *P < 0.05 versus WT (control) mice.