Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas
J. Clin. Invest. Mark Wahrenbrock, et al. 112:853 doi:10.1172/JCI18882 [
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Figure 2Time-course of platelet-rich microthrombi in wild-type mouse lungs following a single injection of mucin. (
a) Typical representations of in vivo platelet-rich microthrombi in lung sections observed using fluorescently labeled Ab against the platelet marker, CD41. (
b) Quantitative histologic determination, quantitating average number of CD41-positive pixels per 200× view field (mean value of 20 random fields). Each bar represents the mean ± SEM. *
P < 0.001 compared with PBS-injected mice,
n = 7; **
P < 0.05,
n = 5.