Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas
J. Clin. Invest. Mark Wahrenbrock, et al. 112:853 doi:10.1172/JCI18882 [
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Figure 1Purified mucin preparations are large and retain calcium-dependent binding sites for all three selectins. (
a) A 4% SDS-PAGE gel with detection of carbohydrates by PAS reagent. (
b) ELISA in which immobilized mucin preparations are probed with recombinant soluble murine selectins. Values represent mean ± SEM;
n = 5 individual mucin preparations. P, P-selectin; L, L-selectin; E, E-selectin.