Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ
J. Clin. Invest. Andrew C. Li, et al. 114:1564 doi:10.1172/JCI18730 [
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Figure 3Gene expression in atherosclerotic lesions determined by real-time PCR analysis. Animals were fed an HC diet for 3 months (resulting in advanced lesions), followed by 4 weeks on the same diet supplemented with the indicated PPAR agonists. Data are expressed as the mean ± SEM of triplicate measurements and are representative of 2 independent experiments. In each case, *
P _ 0.05, **
P _ 0.01, and ***
P _ 0.001, compared with HC. Std, standard.
