Modulation of the molecular composition of large conductance, Ca2+ activated K+ channels in vascular smooth muscle during hypertension
J. Clin. Invest. Gregory C. Amberg, et al. 112:717 doi:10.1172/JCI18684 [
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Figure 4The mRNA levels of β1, but not α, are downregulated in HT cerebral arteries. (
a) Conventional RT-PCR analysis of α and β1 transcript expression in NT and HT arteries. STD = 100-bp marker; NEG = nontemplate control. (
b) Bar plot of the α and β1 transcript abundance in NT and HT smooth muscle as determined by real-time RT-PCR. For each sample, α and β1 amplifications were normalized to the amount of 18S RNA present. See the Methods section for all primer and probe sequences. *
P < 0.05.