Modulation of the molecular composition of large conductance, Ca²⁺ activated K⁺ channels in vascular smooth muscle during hypertension
J. Clin. Invest. Gregory C. Amberg, et al. 112:717 doi:10.1172/JCI18684 [Go to this article.]

Figure 1
HT cerebral arteries are less sensitive to Ibtx than NT cerebral arteries. (a) Representative arterial diameter records from pressurized (60 mmHg) NT (black) and HT (red) arteries before and after the application of Ibtx (300 nM). Before the addition of Ibtx, the diameter of the HT and NT pressurized arteries were, respectively, 87 μm (passive diameter = 146 μm) and 130 μm (passive diameter = 148 μm). (b) Mean ± SEM of Ibtx-induced constriction in NT and HT arteries. (c) Mean ± SEM of KCl-induced (60 mM) constriction in NT and HT arteries. *P < 0.05.