Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent
J. Clin. Invest. Theresa Berndt, et al. 112:785 doi:10.1172/JCI18563 [Go to this article.]

Figure 4
The effect infusion of vehicle (VEH) or sFRP-4 (0.3 μg/kg/h) for 8 hours, or the effect of phosphate deprivation induced by a low-phosphate diet phosphate (LPD) compared with a normal-phosphate diet (NPD), on the concentration of 25-hydroxyvitamin D 1α-hydroxylase cytochrome P450 mRNA concentrations in kidney.*P < 0.05. 25(OH)D, 25-hydroxyvitamin D.