Impaired pancreatic growth, β cell mass, and β cell function in E2F1 –/– mice
J. Clin. Invest. Lluis Fajas, et al. 113:1288 doi:10.1172/JCI18555 [
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Figure 2Gene expression analysis in different tissues of E2F1
_/_ or E2F1
+/+ mice. Quantification of the expression by real-time RT-PCR of relevant genes for the insulin-sensitivity pathway in WAT (
A) and muscle (
B). Results were normalized by the expression of the 18S ribosomal subunit RNA and expressed as fold changes relative to expression levels in E2F1
+/+ mice. Anec., adiponectin; resist., resistin; PKB, protein kinase B. *Statistically significant differences (ANOVA,
P < 0.005).
