Physiological role for P2X₁ receptors in renal microvascular autoregulatory behavior
J. Clin. Invest. Edward W. Inscho, et al. 112:1895 doi:10.1172/JCI18499 [Go to this article.]

Figure 1
Effect of NF279 on the afferent arteriolar response to increasing RPP. (a) The response to an increase in RPP during the control period (open circles) and during exposure to 20 μM NF279 (filled circles). The response during NF279 administration is overlaid on the control response for comparison. (b) The afferent arteriolar response to elevations in RPP from 100 to 160 mmHg before, during, and after P2X receptor blockade with NF279. The period of exposure to 20 μM NF279 is illustrated by the black line. *P < 0.05 vs. diameter at 100 mmHg.