Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis
J. Clin. Invest. Clare R. Ozawa, et al. 113:516 doi:10.1172/JCI18420 [Go to this article.]

Figure 3
Uniform VEGF production across a broad range of levels by myoblast clones. Clones were selected that ranged in VEGF protein secretion levels from 10% to 325% of the average of the parent VEGF myoblast population; these are designated “10% clone” and “325% clone,” for example. Actual VEGF production is indicated above the bar for each population (as ng/10⁶ cells/day). Error bars indicate the SEM of three replicate measurements per clone or population. Ctrl, LacZ-expressing control myoblasts; Poly. VEGF, original polyclonal VEGF myoblast population from which the clones were derived; ND, not detectable.