Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans
J. Clin. Invest. Chiara Luberto, et al. 112:1080 doi:10.1172/JCI18309 [
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Figure 1Phagocytosis assay of
C. neoformans WT H99 and
GAL7:IPC1 10 strains grown on glucose or galactose medium. Decrease of Ipc1 increases phagocytosis, whereas increase of Ipc1 decreases phagocytosis (
P = 0.004 and 0.003, respectively). Phagocytic index is expressed as the geometric mean of the percentage of yeast cells attached or ingested per number of macrophages per field.
