Angiotensin II–accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice
J. Clin. Invest. Dennis Bruemmer, et al. 112:1318 doi:10.1172/JCI18141 [
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Figure 2Immunohistochemical characterization of atherosclerotic lesions from
ApoE–/–OPN+/+ and
ApoE–/–OPN–/– mice 4 weeks after Ang II infusion. Tissues of the thoracic aorta were analyzed by hematoxylin and eosin staining (
a and
d) or immunohistochemical staining for the presence of macrophages (
b and
e) and T lymphocytes (
c and
f) and counterstained with hematoxylin (×400 magnification).
