Chemokine-mediated recruitment of NK cells is a critical host defense mechanism in invasive aspergillosis
J. Clin. Invest. Brad E. Morrison, et al. 112:1862 doi:10.1172/JCI18125 [Go to this article.]

Figure 4
Effect of MCP-1/CCL2 neutralization on NK cells in neutropenic mice on day 1 after intratracheal challenge with A. fumigatus conidia. Flow-cytometry data gated on CD45⁺ cells with lymphocyte light-scatter characteristics. Data are representative of two experiments, with a total of five animals per group. PMN depletion/PBS indicates animals treated with RB6-8C5 mAb and PBS and challenged with intratracheal A. fumigatus conidia; PMN depletion/anti–MCP-1 indicates animals treated with RB6-8C5 and anti–MCP-1/CCL2 mAb’s and challenged with intratracheal A. fumigatus conidia.