BAFF selectively enhances the survival of plasmablasts generated from human memory B cells
J. Clin. Invest. Danielle T. Avery, et al. 112:286 doi:10.1172/JCI18025 [
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Figure 1Expression of BAFF-Rs on human B cells. Human splenic B cells were incubated with (
a) soluble BAFF or mAb specific for (
b) BAFF-R, (
c) TACI, or (
d) BCMA. These results represent experiments performed using B cells from three to five different donor spleens. (
e and
f) 293T cells were transiently transfected with cDNA encoding human (
e) BCMA or (
f) TACI. Expression of the transfected protein was assessed using the anti-BCMA and anti-TACI mAb’s described in
c and
d. For each plot, the thick and thin lines represent the fluorescence of cells incubated with the specific or control reagent, respectively.
