HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P₃
J. Clin. Invest. Jerzy-Roch Nofer, et al. 113:569 doi:10.1172/JCI18004 [Go to this article.]

Figure 4
Vasodilatory effects of HDL, SPC, S1P, and LSF in vivo. Original tracing of MAP in a rat with endothelin-induced elevation of MAP (500 ng bolus + 1,000 ng/h intravenously) after intra-aortic injection (arrows) of HDL (1 mg), S1P (200 nmol), SPC (200 nmol), LSF (200 nmol), or acetylcholine (ACH, 200 nmol).