Bacillus anthracis lethal toxin induces TNF-α–independent hypoxia-mediated toxicity in mice
J. Clin. Invest. Mahtab Moayeri, et al. 112:670 doi:10.1172/JCI17991 [Go to this article.]

Figure 5
Histopathological analysis of LT-treated BALB/cJ liver. (a) Liver from PA-injected (48 hours) control. 10× objective. (b) Centrilobular coagulative necrosis (right) with normal liver and sparing of portal region (upper left) at 24 hours after LT treatment. 20× objective. (c) Poorly formed thrombus at 24 hours. 10× objective. (d) Advanced liver necrosis (right) with continued sparing of portal region (lower left) at 48 hours. 40× objective. Dosage was 100 μg PA (control) or 100 μg LT.