Mice deficient in α-actinin-4 have severe glomerular disease
J. Clin. Invest. Claudine H. Kos, et al. 111:1683 doi:10.1172/JCI17988 [Go to this article.]

Figure 5
Immunofluorescence studies of kidneys from Actn4^–/– mice and Actn4^+/+ littermates (×40 magnification). Antibodies to nephrin, podocin, and type IV collagen (col IV) have been previously described (11). Mice were 5.5 weeks of age at the time of sacrifice, and Actn4^–/– mice had mild proteinuria.