VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
J. Clin. Invest. Yunjuan Sun, et al. 111:1843 doi:10.1172/JCI17977 [
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Figure 3Scheme for quantifying postischemic neurogenesis in the rat brain. MCAO was induced on day 0, VEGF (given by the intracerebroventricular route as shown in upper left) and BrdU (given by the intraperitoneal route) were administered on days 1–3, and rats were killed and brains sectioned for BrdU immunohistochemistry and cell counting on days 3, 7, 14, and 28. OB, olfactory bulb; Ctx, cerebral cortex; LV, lateral ventricle; Hp, hippocampus.
