Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics
J. Clin. Invest. Patrick Flood-Page, et al. 112:1029 doi:10.1172/JCI17974 [
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Figure 1(
a) A comparison of tenascin, lumican, and procollagen III expression in the reticular basement membrane between normal controls (
n = 10) and asthmatic individuals (
n = 11) before and after anti–IL-5. N denotes normal subjects. The crossbars represent the median values. (
b) A comparison of the number of MBP
+ eosinophils in the bronchial mucosa of normal controls and asthmatic subjects at baseline. (
c) The correlation between eosinophil numbers and thickness of tenascin in the reticular basement membrane at baseline.