P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries
J. Clin. Invest. Patrick André, et al. 112:398 doi:10.1172/JCI17864 [
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Figure 7Level of platelet activation at the apex of arterial thrombi. Thrombi formed after a 2.5-minute perfusion period of WT (
a,
c, and
e) and
P2Y12–/– (
b,
d, and
f) blood at 840/s over collagen. Fixed (but not permeabilized) thrombi were stained for P-selectin (
a and
b), Gas6 (
c and
d), and with Alexa 488-fibrinogen (
e and
f).